Search Clinical Trials
Before medications are approved by the U.S. Food and Drug Administration (FDA) or before certain therapy methods are widely accepted as effective, they are tested on people who volunteer to participate in a clinical trial.
Organizations across the country are looking for people like you to take part in their research studies. The list of studies below have been selected from ClinicalTrials.gov based on their inclusion of one or more of the following terms: anxiety disorders, depression, OCD, PTSD, and bipolar disorder.
The Anxiety and Depression Association of America (ADAA) is supportive of research that is conducted through clinical trials. Participating in research can potentially help change the mental health outcomes for you and others who suffer anxiety, depression, and related disorders. You may learn about new interventions/treatments that are being considered. This website page is brought to you in partnership with ResearchMatch.
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PTSD Prevention Using Oral Hydrocortisone
Rachel Yehuda
PTSD
Acute Stress Disorder
Trauma-related Stressor
There is currently no evidence-based intervention for individuals exposed to trauma that
is designed to aid recovery and prevent the development of post-traumatic stress disorder
(PTSD). This randomized control trial proposes to test a one-time prophylactic treatment
for the prevention of symptoms... expand
There is currently no evidence-based intervention for individuals exposed to trauma that is designed to aid recovery and prevent the development of post-traumatic stress disorder (PTSD). This randomized control trial proposes to test a one-time prophylactic treatment for the prevention of symptoms of PTSD and related mental health disturbances and the promotion of resilience using a single dose of hydrocortisone (HCORT) or placebo, administered within six hours of trauma exposure. People at risk for PTSD have demonstrated low cortisol levels before and in the aftermath of traumatic exposures and lower cortisol levels have also been observed in combat veterans with PTSD. Administering HCORT at the time of trauma would help boost the body's natural stress recovery systems to facilitate resilience. Participants who present to the emergency department following trauma exposure and report high distress, panic, anxiety or dissociation will be invited to participate in this clinical trial. 220 trauma survivors will be randomized and recruited at two locations: Mount Sinai Hospital in New York City, US, and a civilian/military hospital in Tel Hashomer, Israel. Trauma survivors will be assessed at 2, 6, 12 and 28 weeks post-treatment. HCORT closely resembles cortisol produced in the adrenal glands and released during stress. It is hypothesized that HCORT treatment will result in an accelerated decline in the presence and severity of PTSD and related mental health symptoms compared to the placebo group. Blood samples will be collected for analysis of potential biomarkers to obtain more information about the mechanisms of action of this intervention. The information obtained will be relevant in determining whether early intervention with a single dose of HCORT, compared to placebo, administered within several hours following trauma exposure, will reduce the risk of developing PTSD in trauma survivors. Type: Interventional Start Date: Jan 2022 |
Study of Dextromethorphan in OCD and Related Disorders
Stanford University
Obsessive-Compulsive Disorder
Illness Anxiety Disorder
Body Dysmorphic Disorders
Somatic Symptom Disorder
The purpose of the study is to assess the tolerability and efficacy of dextromethorphan
in combination with fluoxetine for symptom relief in OCD and related disorders. expand
The purpose of the study is to assess the tolerability and efficacy of dextromethorphan in combination with fluoxetine for symptom relief in OCD and related disorders. Type: Interventional Start Date: Jan 2022 |
Radiation Oncology Patient Medical Physics Intervention Study
The University of Texas Health Science Center at San Antonio
Anxiety
Patient Satisfaction
Radiation Therapy
This investigation is designed to be a two-arm, non-randomized prospective phase 2 study
evaluating the impact of medical physicist patient intervention on the anxiety level and
patient satisfaction of patients undergoing a course of radiation therapy. The goal is to
demonstrate that these interventions... expand
This investigation is designed to be a two-arm, non-randomized prospective phase 2 study evaluating the impact of medical physicist patient intervention on the anxiety level and patient satisfaction of patients undergoing a course of radiation therapy. The goal is to demonstrate that these interventions will have a significantly positive impact on the overall well-being of the oncology patients. Type: Interventional Start Date: Mar 2020 |
A Neuroimaging Study of Open-label Placebo in Depressed Adolescents
University of California, San Francisco
Depression
Major depressive disorder (MDD) is the current leading cause of disability worldwide and
adolescence is an especially vulnerable period for the onset of depression.
Non-pharmacologic approaches are particularly attractive as treatment of adolescent
depression due to the elevated risks of side effects... expand
Major depressive disorder (MDD) is the current leading cause of disability worldwide and adolescence is an especially vulnerable period for the onset of depression. Non-pharmacologic approaches are particularly attractive as treatment of adolescent depression due to the elevated risks of side effects related to the use of psychotropic drugs during development. A recent meta-analysis detected a positive and significant effect of non-deceptive placebos (open-label placebo, OLP) for a series of clinical conditions, including adult depression. To the investigators' knowledge, no studies of OLP have been conducted in depressed adolescents to date, although placebo response rates in adolescent depression are especially high, accounting for over 80% of the actual response to antidepressant treatment. The study's main objective is to estimate the effectiveness and understand the mechanism of OLP in depressed adolescents. The central hypothesis is that the mechanism by which OLP exerts its action in adolescent depression is by forming a positive expectation, which activates endogenous mu-opioid receptor (MOR)-mediated neurotransmission in a network of regions implicated in emotion, stress regulation, and the pathophysiology of MDD, namely, the anterior cingulate cortex (ACC) - striato - amygdalo - thalamic network. The hypothesis has been formulated on the basis of published research and preliminary data. The investigators will test the hypothesis by performing structural and functional neuroimaging in 60 untreated 13-18 year-old adolescents with mild to moderate depression. The proposed research is significant, because it is expected to elucidate the mechanism of action of OLP and advance the understanding of the neural underpinnings of positive expectations in adolescent depression. Type: Interventional Start Date: May 2020 |
Reaching Out to Distressed Medical Residents, Fellows and Faculty
Oregon Health and Science University
Depression
Suicide
The purpose of this study is to study whether distressed medical residents, fellows, and
faculty health professionals benefit from completing online an anonymous and interactive
screening of stress, depression, substance use, and suicidal thoughts. The screening and
ability to interact online with... expand
The purpose of this study is to study whether distressed medical residents, fellows, and faculty health professionals benefit from completing online an anonymous and interactive screening of stress, depression, substance use, and suicidal thoughts. The screening and ability to interact online with a clinician anonymously are hypothesized to increase willingness to come for counseling in person. Suicide risk factors are expected to be lower once the distressed medical trainee or faculty member receives treatment. Type: Interventional Start Date: Jan 2014 |
Acceptability and Feasibility of Transcranial Magnetic Stimulation (TMS) for Depression in Multiple Sclerosis
University of Utah
Multiple Sclerosis
Major Depressive Disorder
Treatment Resistant Depression
The goal of this single-arm, observational pilot study is to learn about the safety,
feasibility, preliminary efficacy of TMS for the treatment of depression in people with
MS. Participants will receive outpatient TMS treatment over the course of 5-6 weeks.
Participants will complete validated questionnaires... expand
The goal of this single-arm, observational pilot study is to learn about the safety, feasibility, preliminary efficacy of TMS for the treatment of depression in people with MS. Participants will receive outpatient TMS treatment over the course of 5-6 weeks. Participants will complete validated questionnaires and exams before, during, and after treatment. Type: Observational Start Date: Jan 2024 |
Augmenting Benzodiazepine Receptor Agonist Deprescribing With Acupuncture and Yoga Among Older Adults
Vanderbilt University Medical Center
Anxiety
Insomnia
Benzodiazepine
Deprescription
The main purpose of this 12-week study is to see if a new combination of treatments can
help older adults reduce benzodiazepine or related medication use. The treatment
combination consists of 1) medical provider visits to gradually reduce the medication
dose over 12 weeks, 2) acupuncture treatments,... expand
The main purpose of this 12-week study is to see if a new combination of treatments can help older adults reduce benzodiazepine or related medication use. The treatment combination consists of 1) medical provider visits to gradually reduce the medication dose over 12 weeks, 2) acupuncture treatments, and 3) private yoga classes. Participants will be offered weekly visits for 12 weeks to receive combined treatments. Participants will be provided surveys before, during, and after the study to learn about their experience of the treatments. At the end of the study, participants will be invited to participate in a focus group to learn about their experience in the study. Type: Interventional Start Date: Dec 2023 |
Families With Pride ("Familias Con Orgullo").
University of Miami
Depression
Drug Use
This study will evaluate the effects of a parenting intervention for Hispanic sexual
minority youth in preventing/reducing drug use and depressive symptoms. It will also
examine whether the intervention improves parent social support for the adolescent,
parent acceptance, family functioning, and whether... expand
This study will evaluate the effects of a parenting intervention for Hispanic sexual minority youth in preventing/reducing drug use and depressive symptoms. It will also examine whether the intervention improves parent social support for the adolescent, parent acceptance, family functioning, and whether it reduces general stress and stress associated with being a Hispanic sexual minority. Type: Interventional Start Date: Mar 2024 |
TEAM-Red, a Remotely Delivered Self-management Program for Depressed Black Women At Risk for Hypertension
Jennifer B. Levin
Depression
The proposed project is a 24-week prospective randomized controlled trial (RCT)
evaluating the effects of TargEted MAnageMent Intervention (TEAM, N=25) vs. enhanced
wait-list (eWL, N=25) control in depressed young (<50 years) African-American (AA) women
at risk for hypertension. expand
The proposed project is a 24-week prospective randomized controlled trial (RCT) evaluating the effects of TargEted MAnageMent Intervention (TEAM, N=25) vs. enhanced wait-list (eWL, N=25) control in depressed young (<50 years) African-American (AA) women at risk for hypertension. Type: Interventional Start Date: Jan 2023 |
The Effect of Hyperoxia on Ventilation During Recovery From General Anesthesia
Stanford University
Ventilatory Depression
Postoperative Respiratory Failure
In this randomized-controlled trial the investigators will examine the effect of oxygen
supplementation on the recovery of breathing for 90 minutes in the immediate
post-anesthesia period starting from extubation of the trachea. expand
In this randomized-controlled trial the investigators will examine the effect of oxygen supplementation on the recovery of breathing for 90 minutes in the immediate post-anesthesia period starting from extubation of the trachea. Type: Interventional Start Date: Oct 2022 |
ERP to Improve Functioning in Veterans With OCD
VA Office of Research and Development
Obsessive Compulsive Disorder (OCD)
Comorbid Post-Traumatic Stress Disorder and OCD
Obsessive compulsive disorder (OCD) is a debilitating psychiatric illness impacting work,
social, and family functioning. Exposure and Response Prevention (ERP) is the sole
evidence-based psychotherapy for OCD; however, no randomized controlled trials (RCTs)
have examined the effectiveness of ERP... expand
Obsessive compulsive disorder (OCD) is a debilitating psychiatric illness impacting work, social, and family functioning. Exposure and Response Prevention (ERP) is the sole evidence-based psychotherapy for OCD; however, no randomized controlled trials (RCTs) have examined the effectiveness of ERP among Veterans or individuals with both OCD and posttraumatic stress disorder (PTSD). This 4-year Hybrid Type I trial will compare outcomes of ERP to those of a control condition among Veterans with OCD. Primary and secondary aims will examine whether Veterans' functioning, quality of life, and OCD symptoms differ between the ERP and control in the full sample of Veterans with OCD, and in the half of the sample with both OCD and PTSD. The tertiary aim is to conduct a mixed-methods formative evaluation of the implementation potential of ERP in VA mental health settings. Type: Interventional Start Date: Oct 2022 |
ICBT (Internet Based Cognitive Behavioral Therapy) for Maternal Depression: Community Implementation...
Oregon Research Institute
Depression
Low income women of childbearing age are at increased risk for depression and often do
not receive needed treatment. Investigators developed Mom-Net, an on-line cognitive
behavioral treatment (CBT) for depression to address the needs of low income women of
childbearing age. The intervention program... expand
Low income women of childbearing age are at increased risk for depression and often do not receive needed treatment. Investigators developed Mom-Net, an on-line cognitive behavioral treatment (CBT) for depression to address the needs of low income women of childbearing age. The intervention program also includes live coaching to help the mothers engage and learn the CBT material. Mom-Net has been shown to be highly effective in reducing depressive symptoms and improving parenting behavior and child adjustment, in earlier controlled trials. In this project the investigators are examining whether access to Mom-Net can be expanded by delivering it in Head Starts (HS). To address that broad question, the investigators will focus on two sets of scientific questions: 1. Implementation Questions: e.g., Can HS agencies deliver the program successfully; do HSs choose to sustain the program after the research project ends; what agency characteristics are associated with successful delivery of Mom-Net); 2. Effectiveness Questions: e.g., Does Mom-Net reduce maternal depression when delivered by Head Start agencies, with HS staff doing the coaching? Head Start agencies will be randomized to deliver either Mom-Net with the usual high-intensity coaching or with a low-intensity coaching alternative. Within each agency, depressed mothers will be randomized to receive either: 1) Mom-Net program; or 2) Treatment as Usual (TAU;) referral to community mental health providers). Mothers initially assigned to the TAU condition, will have the option of receiving Mom-Net at a later date. Mothers will participate in assessments of depressive symptoms, parenting behavior, and child adjustment at Time 1 (T1; prior to randomization); and Time 2 (T2; after the intervention period) and Time 3 (T3; one year after T1). Type: Interventional Start Date: Dec 2022 |
Neural Circuit Biomarkers of Transcranial Magnetic Stimulation Study
Stanford University
Depression
This study is currently recruiting Veterans only. The objective of this observational
study is to test whether neuroimaging biomarkers of repetitive transcranial magnetic
stimulation (TMS) can be prospectively replicated in a large ecologically valid sample.
We focus on cognitive network connectivity... expand
This study is currently recruiting Veterans only. The objective of this observational study is to test whether neuroimaging biomarkers of repetitive transcranial magnetic stimulation (TMS) can be prospectively replicated in a large ecologically valid sample. We focus on cognitive network connectivity as a predictive biomarker of the clinical effect of TMS, and as a response biomarker of change with TMS. We address this objective through a pragmatic approach in which we recruit patients undergoing routine clinical care and program evaluation in a Veterans Administration multi-site clinical TMS program. Type: Observational Start Date: Nov 2020 |
Brief, High-dose rTMS for Depression
Medical University of South Carolina
Depression
Anxiety
High frequency repetitive transcranial magnetic stimulation (rTMS) has been shown to be
safe, feasible, and acceptable. Conventionally, rTMS investigations have relied on
rational decision trees for dosage determination. The purpose of this study is to
systematically examine an accelerated protocol... expand
High frequency repetitive transcranial magnetic stimulation (rTMS) has been shown to be safe, feasible, and acceptable. Conventionally, rTMS investigations have relied on rational decision trees for dosage determination. The purpose of this study is to systematically examine an accelerated protocol of intermittent theta burst (iTBS). Study 1 aims to provide a quantifiable dose-response curve for iTBS and depressive symptom reduction in major depression. Study 2 aims to determine the role of individual variations of their functional networks compared to the site of stimulation and clinical outcomes. Type: Interventional Start Date: May 2021 |
A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness...
LivaNova
Treatment Resistant Depression
Objectives of this study are to determine whether active VNS Therapy treatment is
superior to a no stimulation control in producing a reduction in baseline depressive
symptom severity, based on multiple depression scale assessment tools at 12 months from
randomization. expand
Objectives of this study are to determine whether active VNS Therapy treatment is superior to a no stimulation control in producing a reduction in baseline depressive symptom severity, based on multiple depression scale assessment tools at 12 months from randomization. Type: Interventional Start Date: Sep 2019 |
Exparel vs. ACB With Bupivacaine for ACL Reconstruction
Children's Hospital of Orange County
ACL Tear
Opioid Misuse
Pain
Anxiety
Opioid misuse and addiction among children and adolescents is an increasingly concerning
problem. Post-surgical opioid prescriptions for commonly performed surgeries such as
anterior cruciate ligament reconstruction (ACLR) increase opioid exposure in young
athletes. The purpose of the current study... expand
Opioid misuse and addiction among children and adolescents is an increasingly concerning problem. Post-surgical opioid prescriptions for commonly performed surgeries such as anterior cruciate ligament reconstruction (ACLR) increase opioid exposure in young athletes. The purpose of the current study is to determine if extended-release Bupivacaine Liposome Injectable Suspension (Exparel) is effective in decreasing at home narcotic consumption compared to standard Bupivacaine Adductor Canal Block for Anterior Cruciate Ligament (ACL) reconstruction/reconstruction for the surgical treatment of adolescents with ACL tears and concomitant pathology i.e. meniscus / cartilage injury/tear. Type: Interventional Start Date: Oct 2023 |
Modulating Escape Using Focused Ultrasound
Medical University of South Carolina
Anxiety Disorders
This is a study to find out if a cutting-edge technology called transcranial focused
ultrasound (tFUS) can be used to treat how people with anxiety or related concerns cope
with emotional situations. tFUS is a brain stimulation technology that causes temporary
changes in the activity of deep brain... expand
This is a study to find out if a cutting-edge technology called transcranial focused ultrasound (tFUS) can be used to treat how people with anxiety or related concerns cope with emotional situations. tFUS is a brain stimulation technology that causes temporary changes in the activity of deep brain areas without a need for any surgery or other permanent or invasive procedures. This study is recruiting participants who recently started treatment for anxiety or a related concern to come in for 3 visits at the Medical University of South Carolina. At the first visit, participants will do interviews and surveys asking about anxiety and related concerns, and they do tasks where they respond to emotional pictures while brain activity is measured using magnetic resonance imaging (MRI). At the next two visits, participants again do a task where they see and react to emotional images, and this time the task is done once before and again once after receiving tFUS that either actively causes temporary changes (lasting for about an hour) in a targeted brain area or is not active (no changes elicited). At each tFUS visit, responses are measured with sensors worn on the hand, arms, face, and head (these visits do not involve MRI). Each visit in this study is expected to last between 2 - 3 hours. This study is not a treatment study, but it could help improve treatment in the future. Participants in this study are paid for their time. Type: Interventional Start Date: May 2024 |
Evaluating Process of Change in Cognitive Behavioral Therapy and Acceptance and Commitment Therapy for...
University of Southern California
Depression
This study will compare two psychological treatments for major depressive disorder (MDD):
cognitive-behavioral therapy (CBT) and acceptance and commitment therapy (ACT). Both
treatments are well-studied and supported by evidence as effective options for people
experiencing depression. These treatments... expand
This study will compare two psychological treatments for major depressive disorder (MDD): cognitive-behavioral therapy (CBT) and acceptance and commitment therapy (ACT). Both treatments are well-studied and supported by evidence as effective options for people experiencing depression. These treatments will be delivered in an online group format via Zoom. The study will enroll up to 150 participants with depression. Half of the participants will receive online group CBT and half will receive online group ACT. There will be up to 10 members in each group. For both conditions, treatment will be provided over 8 weeks, with a 6-month follow-up period. Enrollment will be ongoing and groups will occur simultaneously. Potential participants are asked to complete an initial screening and an intake evaluation to determine eligibility. They will then receive 8-weeks of treatment. Participants will complete self-report questionnaires throughout their time in the study. Type: Interventional Start Date: Jan 2024 |
Better Sleep Study
University of California, San Francisco
Depression in Adolescence
Delayed Sleep Phase
The overall aim of this proposal is a confirmatory efficacy trial sufficiently powered
and designed to test the hypothesis that improving the relationship between biological
circadian timing and waketime, a novel modifiable target, improves depression outcomes in
a subgroup of adolescents with depression... expand
The overall aim of this proposal is a confirmatory efficacy trial sufficiently powered and designed to test the hypothesis that improving the relationship between biological circadian timing and waketime, a novel modifiable target, improves depression outcomes in a subgroup of adolescents with depression and a misaligned relationship between biological circadian timing and waketime utilizing a cognitive-behavioral sleep intervention. Type: Interventional Start Date: Mar 2024 |
Examining Neurobiological Mechanisms Underlying the Therapeutic Effect of the Ketogenic Diet in Bipolar...
University of Pittsburgh
Bipolar Disorder
The investigators aim to examine the effect of the ketogenic diet on brain activity,
metabolism, and emotions in adults with Bipolar Disorder (BD). expand
The investigators aim to examine the effect of the ketogenic diet on brain activity, metabolism, and emotions in adults with Bipolar Disorder (BD). Type: Interventional Start Date: Jan 2024 |
A Mobile Application for Child-focused Perioperative Education
Children's Healthcare of Atlanta
Preoperative Anxiety
The investigators developed a child-friendly mobile application to support accessible,
interactive patient/caregiver education about pediatric tonsillectomy. This randomized
controlled trial aims to evaluate whether the intervention reduces preoperative anxiety,
improves patients' confidence and positive... expand
The investigators developed a child-friendly mobile application to support accessible, interactive patient/caregiver education about pediatric tonsillectomy. This randomized controlled trial aims to evaluate whether the intervention reduces preoperative anxiety, improves patients' confidence and positive coping, improves caregivers' satisfaction and self-efficacy, and reduces call volumes from caregivers to the clinic after surgery compared to current standard care. Type: Interventional Start Date: Feb 2024 |
Inflammation and Depression in People With HIV
Emory University
HIV
Depression
Anhedonia
The purpose of this 10-week, double-blind, placebo-controlled study is to determine
whether inflammation impacts reward and motor neural circuitry to contribute to
depressive symptoms like anhedonia and psychomotor slowing in people with Human
Immunodeficiency Virus (HIV) and depression. Sixty male... expand
The purpose of this 10-week, double-blind, placebo-controlled study is to determine whether inflammation impacts reward and motor neural circuitry to contribute to depressive symptoms like anhedonia and psychomotor slowing in people with Human Immunodeficiency Virus (HIV) and depression. Sixty male and female patients with HIV who have depression, anhedonia and high inflammation and are stable on effective treatment for their HIV will be randomized to receive either the anti-inflammatory drug baricitinib or a placebo for 10 weeks. Participants will complete lab tests, medical and psychiatric assessments, neurocognitive testing, functional MRI (fMRI) scans, and optional spinal taps as part of the study. The total length of participation is about 5 months. Type: Interventional Start Date: Dec 2023 |
Behavioral Activation and Medication Optimization For Improving Perioperative Mental Health In Older...
Washington University School of Medicine
Older Adults
Anxiety
Depression
Major Surgical Resection of a Thoracic Malignancy
Major Surgical Resection of an Abdominal Malignancy
Using a Hybrid Type 1 Effectiveness-Implementation randomized control trial (RCT) design,
the investigators will test the effectiveness of a bundled behavioral activation and
medication optimization in reducing symptoms of depression and anxiety in older adults
undergoing oncologic surgery (compared... expand
Using a Hybrid Type 1 Effectiveness-Implementation randomized control trial (RCT) design, the investigators will test the effectiveness of a bundled behavioral activation and medication optimization in reducing symptoms of depression and anxiety in older adults undergoing oncologic surgery (compared with usual care), while examining implementation outcomes. Type: Interventional Start Date: Mar 2023 |
Treatments in Women Veterans With Insomnia and PTSD
VA Office of Research and Development
Insomnia
PTSD
Women Veterans
This pilot trial will compare trauma-informed Cognitive Behavioral Therapy for Insomnia
(CBT-I) to a psychoeducational intervention in women Veterans with comorbid insomnia and
posttraumatic stress disorder (PTSD). The CBT-I intervention includes trauma-informed
adaptations to an insomnia treatment... expand
This pilot trial will compare trauma-informed Cognitive Behavioral Therapy for Insomnia (CBT-I) to a psychoeducational intervention in women Veterans with comorbid insomnia and posttraumatic stress disorder (PTSD). The CBT-I intervention includes trauma-informed adaptations to an insomnia treatment and the psychoeducational intervention is modeled after usual care in a VA Women's Mental Health Clinic. The study objectives are to: 1) Iteratively refine the structure and materials of trauma-informed CBT-I in preparation for a pilot trial, 2) Pilot test the effects of trauma-informed CBT-I on PTSD treatment readiness and engagement in a sample of women Veterans, and 3) Examine potential mechanisms underlying variations in PTSD treatment readiness and engagement over time among women Veterans. Women Veterans with insomnia and comorbid PTSD who receive care at Sepulveda and West Los Angeles facilities will be recruited for the study. Those who pass an initial eligibility screen will be enrolled and written informed consent will be obtained. A baseline assessment will be completed that includes measures of PTSD treatment readiness, perceived barriers to PTSD treatment, and sleep and mental health symptoms. Then Veterans who meet all eligibility criteria will be randomly assigned to trauma-informed CBT-I (n=25) or the psychoeducational intervention (n=25). Both treatments will be provided in 5 one-on-one sessions by a trained instructor who is supervised by a behavioral sleep medicine specialist. All randomized participants (n=50) will have 2 follow-up assessments (post-treatment and 3-months). The follow-up assessments will collect information on PTSD treatment readiness, perceived barriers to PTSD treatment, and sleep and mental health symptoms. Chart reviews will be conducted 6-months post-treatment to assess number of PTSD treatment appointments attended (treatment engagement measure). Qualitative interviews will be conducted to identify mechanisms underlying PTSD treatment engagement. Type: Interventional Start Date: Jun 2023 |
Behavioral Activation and Medication Optimization In Older Adults Undergoing Cardiac Procedures
Washington University School of Medicine
Cardiac Surgery
Older Adults
Depression
Anxiety
This Hybrid 1 Study will test the effectiveness of a bundled intervention comprised of
behavioral activation and medication optimization in reducing symptoms of depression and
anxiety in older adults undergoing cardiac surgery (compared with usual care), while
examining implementation outcomes. expand
This Hybrid 1 Study will test the effectiveness of a bundled intervention comprised of behavioral activation and medication optimization in reducing symptoms of depression and anxiety in older adults undergoing cardiac surgery (compared with usual care), while examining implementation outcomes. Type: Interventional Start Date: Nov 2022 |
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