Search Clinical Trials
Before medications are approved by the U.S. Food and Drug Administration (FDA) or before certain therapy methods are widely accepted as effective, they are tested on people who volunteer to participate in a clinical trial.
Organizations across the country are looking for people like you to take part in their research studies. The list of studies below have been selected from ClinicalTrials.gov based on their inclusion of one or more of the following terms: anxiety disorders, depression, OCD, PTSD, and bipolar disorder.
The Anxiety and Depression Association of America (ADAA) is supportive of research that is conducted through clinical trials. Participating in research can potentially help change the mental health outcomes for you and others who suffer anxiety, depression, and related disorders. You may learn about new interventions/treatments that are being considered.
Read this ADAA blog about things to know and questions to ask before committing to a clinical trial.
This website page is brought to you in partnership with ResearchMatch.
Sponsor Condition of Interest |
---|
Approach-Avoidance, Computational Framework for Predicting Behavioral Therapy Outcome (AAC-BeT)
Laureate Institute for Brain Research, Inc.
Anxiety
Depression
Depression and anxiety disorders rank in the top ten causes of years lived with
disability. Less than 50% of patients experiencing long-lasting improvements to current
gold-standard treatments. Two gold-standard behavioral interventions include behavioral
activation, focused on enhancing approach... expand
Depression and anxiety disorders rank in the top ten causes of years lived with disability. Less than 50% of patients experiencing long-lasting improvements to current gold-standard treatments. Two gold-standard behavioral interventions include behavioral activation, focused on enhancing approach behavior towards meaningful activities, and exposure-based therapy, focused on decreasing avoidance and challenging negative expectations. While these interventions have divergent treatment targets, there is little knowledge to inform which strategies should be used in the frequent case of comorbid anxiety and depression. Approach-avoidance decision-making paradigms focus on assessing responses when faced with potential rewards and threats, tapping into processes important for both anxiety and depression as well as behavioral activation and exposure-based therapy. For this study, investigators will recruit individuals reporting both anxiety and depression symptoms and randomize them to one of three different interventions: (1) behavioral activation, (2) exposure-based therapy, and a non-specific therapy approach (3) supportive therapy. Participants will complete clinical, self-report, behavioral, and functional magnetic resonance imaging (fMRI) assessments before and after therapy. Investigators will use a computational approach to model factors that may influence one's behavior during approach-avoidance decision-making, including drives to avoid threat versus approach reward and confidence versus uncertainty in one's decisions. This project will accomplish the following aims (1) Determine how changes in brain and behavior responses during approach-avoidance conflict relate to changes in mental health symptoms with the different therapy approaches, (2) Determine the degree to which baseline brain and behavior responses during approach-avoidance conflict predict response to the different therapy approaches, above and beyond the influence of demographics and baseline symptom severity. In addition, by including peripheral blood draws and measures of grace matter volume, the project will also accomplish the following aims: (1) Determine whether kynrenine metabolites measures peripherally may be beneficial as a biomarker of treatment response and (2) determine whether there is an association between change in kynurenine metabolites and changes in gray matter volume with treatment. Results will enhance understanding of how different psychotherapy approaches (behavioral activation, exposure-based therapy) may impact brain responses and decisions when faces with potential reward versus threat and approach versus avoidance drives. In addition, results will have important implications concerning the potential for a more personalized approach to psychotherapy, enhancing knowledge of which types of therapy strategies may be most beneficial for which individuals. Type: Interventional Start Date: Sep 2020 |
Building an Outcomes Assessment Infrastructure to Assess Anxiety Treatment
Mclean Hospital
Social Anxiety Disorder
Specific Phobia
Separation Anxiety Disorder
Panic Disorder
Agoraphobia
The collection of patient self-report and diagnostic data will allow us to examine the
efficacy of the treatment delivered in the McLean Anxiety Mastery Program. Using data
gathered through routine clinical care, the investigators seek to explore whether
patients in treatment show improvements from... expand
The collection of patient self-report and diagnostic data will allow us to examine the efficacy of the treatment delivered in the McLean Anxiety Mastery Program. Using data gathered through routine clinical care, the investigators seek to explore whether patients in treatment show improvements from admission to discharge, compared to patients on the waitlist, and whether these gains are maintained three months post-discharge. The following are included as examples of some of the study's hypotheses. Type: Interventional Start Date: Oct 2014 |
Low-Dose Intravenous Ketamine for Adolescents With Depression and Suicidal Ideation in the Emergency...
Rady Children's Hospital, San Diego
Depression
Suicidal Ideation
The goal of this study is to test whether a single low-dose of IV ketamine given in the
emergency department to adolescents with treatment-resistant depression and suicidal
ideation can reduce depression symptoms and suicidal thoughts compared to placebo.
Participants will complete depression scales... expand
The goal of this study is to test whether a single low-dose of IV ketamine given in the emergency department to adolescents with treatment-resistant depression and suicidal ideation can reduce depression symptoms and suicidal thoughts compared to placebo. Participants will complete depression scales at baseline, and 1 hour, 3 hours, 1 day, 3 days, and 7 days after receiving the treatment. Type: Interventional Start Date: Mar 2022 |
AIMS Medical Outcomes Study
Advanced Integrative Medical Science Institute
Mental Health Issue
PTSD
Pain
Chronic Pain
Chronic Disease
This epidemiologic research is being conducted as an observational prospective case
series outcomes study of the use of advanced integrative specialty medical care and its
effect on adult and pediatric patients with chronic or serious illnesses or mental health
disorders. expand
This epidemiologic research is being conducted as an observational prospective case series outcomes study of the use of advanced integrative specialty medical care and its effect on adult and pediatric patients with chronic or serious illnesses or mental health disorders. Type: Observational Start Date: Jul 2020 |
Nitrous Oxide for the Treatment of Major Depressive Disorder
Bayside Health
Depression
Major Depressive Disorder
The investigators are conducting a randomized controlled trial to evaluate the
antidepressant effects of nitrous oxide in people with Major Depressive Disorder (MDD).
MDD is a global medical condition that causes significant health and economic burden.
Recent studies have shown that a single dose... expand
The investigators are conducting a randomized controlled trial to evaluate the antidepressant effects of nitrous oxide in people with Major Depressive Disorder (MDD). MDD is a global medical condition that causes significant health and economic burden. Recent studies have shown that a single dose of ketamine, an NMDA-antagonist, has fast and long lasting anti-depressant effect. Nitrous oxide, another NMDA-antagonist, is widely used for anesthesia and analgesia, safer to administer and has fewer side effects than ketamine. A randomized controlled crossover feasibility study showed significant reduction in depressive symptoms at 2 and 24 hours after a single 1-hour treatment session of inhaled nitrous oxide compared with placebo. Nitrous oxide is inexpensive and can be safely administered by any trained clinician. If found to be efficacious, it could be used to provide rapid anti-depressant effect whilst the benefit of traditional anti-depressants has its delayed effect. Another potential application could be in acutely suicidal patients. This investigated-initiated phase 2b trial will enable confirmation and extension of the findings from the feasibility study, and identify the optimal dose and regimen in a broader population of those with MDD. Participants will be randomized to receive a weekly 1-hour inhalational sessions of either nitrous oxide or placebo (oxygen-air mixture) for 4 weeks, and the nitrous group will be further randomly assigned to a dose of 50% nitrous oxide or 25% nitrous oxide. Depression severity will be assessed by a blinded observer pre-treatment and at weekly intervals during and for 4 weeks after treatment using the Hamilton Depression Rating Scale. Type: Interventional Start Date: Jan 2019 |
Transdiagnostic CBT for Comorbid Alcohol Use and Anxiety Disorders
Boston University Charles River Campus
Alcohol Use Disorder
Anxiety Disorders
Almost 18 million US adults have alcohol use disorders (AUD), with one third of these
individuals also diagnosed with anxiety disorders (AXD). The coexistence of AUD and AXD
imposes a high burden via healthcare costs and lost productivity. To date, existing
treatment approaches for addressing AUD/AXD... expand
Almost 18 million US adults have alcohol use disorders (AUD), with one third of these individuals also diagnosed with anxiety disorders (AXD). The coexistence of AUD and AXD imposes a high burden via healthcare costs and lost productivity. To date, existing treatment approaches for addressing AUD/AXD comorbidity have been only modestly effective and there is a lack of adequate research to guide treatment decisions. The Unified Protocol (UP) is a transdiagnostic, cognitive-behavioral therapy that has shown efficacy in treating emotional disorders. The efficacy of the UP to facilitate abstinence from alcohol consumption in individuals with comorbid AUD/AXD has also been examined, with results from this study indicating a reduction from baseline in drinks consumed per day. However, further evaluation of the UP for managing AUD/AXD is warranted. In this clinical trial, the investigators will further assess the UP's effectiveness in reducing alcohol consumption in patients with comorbid AUD/AXD. Participants will be randomized to one of two conditions: 1) treatment with the UP or 2) treatment with therapist-guided Take Control (TC; a computerized alcohol reduction program). In addition, in a subset of twenty-five participants, functional magnetic resonance scanning (fMRI) will be used to examine the effects of the UP on changes in brain activity in areas important to regulation of emotional and reward processes implicated in excessive alcohol consumption. The researchers' primary hypotheses are that the UP group will, compared to the TC group: 1) be superior in acute symptom reduction from pre- to post-treatment, and 2) evidence greater reductions in percent days heavy drinking, percent days of drinking per week, and alcohol craving. Type: Interventional Start Date: Mar 2018 |
PEERS Plus mHealth Enhanced Peer Support
Massachusetts General Hospital
Depression in Old Age
The goal of this intervention study is to design and learn whether peer support that is
delivered through video chats and texting can decrease depression among older adults.
Participants will be assigned to a peer support program where they will receive 8 video
chats with a peer mentor who provide... expand
The goal of this intervention study is to design and learn whether peer support that is delivered through video chats and texting can decrease depression among older adults. Participants will be assigned to a peer support program where they will receive 8 video chats with a peer mentor who provide social support and supportive texts over 8 weeks. Type: Interventional Start Date: Oct 2020 |
Efficacy and Safety Study of BHV-7000 Monotherapy in Major Depression
Biohaven Therapeutics Ltd.
Major Depressive Disorder
The purpose of this study is to determine the efficacy and safety of BHV-7000 in
participants with Major Depressive Disorder (MDD) expand
The purpose of this study is to determine the efficacy and safety of BHV-7000 in participants with Major Depressive Disorder (MDD) Type: Interventional Start Date: May 2024 |
BHV-7000 Acute Treatment of Bipolar Mania
Biohaven Therapeutics Ltd.
Bipolar Disorder
The purpose of this study is to determine whether BHV-7000 is a safe and effective acute
treatment for manic episodes in bipolar disorder I. expand
The purpose of this study is to determine whether BHV-7000 is a safe and effective acute treatment for manic episodes in bipolar disorder I. Type: Interventional Start Date: May 2024 |
A Study to Test Different Doses of BI 1569912 in People With Depression Who Take Anti-depressive Medicine
Boehringer Ingelheim
Depressive Disorder, Major
This study is open to adults between 18 and 65 with a type of depression (major
depressive disorder) for whom previous treatments for depression did not work. The
purpose of the study is to find out whether a medicine called BI 1569912 helps people
with depression.
Participants continue their standard... expand
This study is open to adults between 18 and 65 with a type of depression (major depressive disorder) for whom previous treatments for depression did not work. The purpose of the study is to find out whether a medicine called BI 1569912 helps people with depression. Participants continue their standard therapy throughout the study. Participants are put into 4 groups by chance. 3 of the 4 groups take different doses of BI 1569912. 1 group takes placebo. Placebo tablets looks like BI 1569912 but do not contain any medicine. Participants take the tablets once a day for 6 weeks. Participants are in the study for about 2 to 4 and a half months. During this time, they visit the study site at least 6 times. At the visits, doctors ask participants about their symptoms. The participants answer questions about their depression symptoms. The results are compared between the groups. The doctors also regularly check the general health of participants. Type: Interventional Start Date: Mar 2024 |
A Study of Spoken Language in Mania
Mayo Clinic
Manic Episode
Bipolar I Disorder
This research is being done to find if there are changes with voice and speech during
episodes of mania. expand
This research is being done to find if there are changes with voice and speech during episodes of mania. Type: Interventional Start Date: Apr 2023 |
A Study of Aticaprant 10 Milligrams (mg) as Adjunctive Therapy in Adult Participants With MDD With Moderate-to-severe...
Janssen Research & Development, LLC
Depressive Disorder, Major
Anhedonia
The purpose of this study is to evaluate the efficacy of aticaprant compared with placebo
as adjunctive therapy to an antidepressant in improving depressive symptoms in adult
participants with major depressive disorder (MDD) with moderate to severe anhedonia
(ANH+) who have had an inadequate response... expand
The purpose of this study is to evaluate the efficacy of aticaprant compared with placebo as adjunctive therapy to an antidepressant in improving depressive symptoms in adult participants with major depressive disorder (MDD) with moderate to severe anhedonia (ANH+) who have had an inadequate response to current antidepressant therapy with a selective serotonin reuptake inhibitor (SSRI) or serotonin-norepinephrine reuptake inhibitor (SNRI). Type: Interventional Start Date: Dec 2022 |
Treatment of Post-partum Depression Using an Behavioral Intervention Called ROSE (Reach Out, Stay Strong,...
University of Rochester
Post-partum Depression
A randomized trial of pregnant people at risk for postpartum depression comparing the
InBloom app (n = 76) to ROSE (n = 76; weekly scheduled group), and two control groups. We
will assess Depression at baseline and 1, 2 and 3 months, ROI at 3 months, Satisfaction
at 1 and 3 months and Perceived Access... expand
A randomized trial of pregnant people at risk for postpartum depression comparing the InBloom app (n = 76) to ROSE (n = 76; weekly scheduled group), and two control groups. We will assess Depression at baseline and 1, 2 and 3 months, ROI at 3 months, Satisfaction at 1 and 3 months and Perceived Access at 1 and 3 months. Subject participation will last up to 8 months (minimum 17 weeks pregnant through 3 months postpartum). Type: Interventional Start Date: Jul 2023 |
A Study of Aticaprant in Adult and Elderly Participants With Major Depressive Disorder (MDD)
Janssen Research & Development, LLC
Depressive Disorder, Major
The purpose of this study is to assess the long-term safety and tolerability of
aticaprant administered as adjunctive therapy to a current antidepressant (selective
serotonin reuptake inhibitor [SSRI] or serotonin and norepinephrine reuptake inhibitor
[SNRI]) in all participants with major depressive... expand
The purpose of this study is to assess the long-term safety and tolerability of aticaprant administered as adjunctive therapy to a current antidepressant (selective serotonin reuptake inhibitor [SSRI] or serotonin and norepinephrine reuptake inhibitor [SNRI]) in all participants with major depressive disorder (MDD). Type: Interventional Start Date: Sep 2022 |
TEAM-Red, a Remotely Delivered Self-management Program for Depressed Black Women at Risk for Hypertension
Jennifer B. Levin
Depression
The proposed project is a 24-week prospective randomized controlled trial (RCT)
evaluating the effects of TargEted MAnageMent Intervention (TEAM, N=41) vs. enhanced
waitlist (eWL, N=41) control in young (<50 years) African American women who are
depressed or suffering from stress, and at risk for... expand
The proposed project is a 24-week prospective randomized controlled trial (RCT) evaluating the effects of TargEted MAnageMent Intervention (TEAM, N=41) vs. enhanced waitlist (eWL, N=41) control in young (<50 years) African American women who are depressed or suffering from stress, and at risk for hypertension. Type: Interventional Start Date: Jan 2023 |
Creative Arts Program to Reduce Burnout in Healthcare Professionals
University of Colorado, Denver
Burn-Out Syndrome
Post-Traumatic Stress Disorder
Depression, Anxiety
This study plans to learn if creative arts programs that include visual, musical,
written, or physical expression can reduce symptoms of burnout syndrome, Post Traumatic
Stress Disorder (PTSD), depression, and anxiety in critical care healthcare
professionals. This study also explores if creative... expand
This study plans to learn if creative arts programs that include visual, musical, written, or physical expression can reduce symptoms of burnout syndrome, Post Traumatic Stress Disorder (PTSD), depression, and anxiety in critical care healthcare professionals. This study also explores if creative arts can enhance the connection to the purpose of work, the development of adequate coping skills, while providing time to connect with peers. Type: Interventional Start Date: Mar 2020 |
Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers
National Institute of Mental Health (NIMH)
Mood Disorders
Anxiety Disorders
Healthy Volunteers
Bipolar Disorder
Depression
The purpose of this protocol is to allow for the careful screening of patients and
healthy volunteers for participation in research protocols in the Experimental
Therapeutics and Pathophysiology Lab (ETPB) at the National Institute of Mental Health
(NIMH) and for the collection of natural history... expand
The purpose of this protocol is to allow for the careful screening of patients and healthy volunteers for participation in research protocols in the Experimental Therapeutics and Pathophysiology Lab (ETPB) at the National Institute of Mental Health (NIMH) and for the collection of natural history data. In addition the protocol will allow clinicians to gain more experience in the use of a variety of polysomnographic and high-density EEG recordings. Subjects in this protocol will undergo an evaluation which may include: a psychiatric interview; a diagnostic interview; rating scales; a medical history; a physical exam; brain magnetic resonance imaging (MRI); electroencephalography (EEG); electrocardiography (EKG), magnetoencephalography (MEG); blood, saliva and urine laboratory evaluation; and a request for medical records. Subjects may also be asked to complete questionnaires about attitudes towards research and motivation for research participation. The data collected may also be linked with data from other mood and anxiety disorder protocols (e.g., brain imaging, DNA, psychophysiology tests, treatment studies, etc) for the purposes of better understanding the diagnosis, pathophysiology, and treatment response of patients with mood disorders. Parents of minors will be interviewed. Upon conclusion of the screening process, subjects will either be offered participation in a research protocol and will sign the appropriate informed consent, or will be considered not appropriate for participation in research and will be referred back into the community. The current protocol thus serves as an entry point for individuals with mood or anxiety disorders or healthy volunteers to enter NIMH IRB approved ETPB protocols. Type: Observational Start Date: Feb 2001 |
Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders
National Institute of Mental Health (NIMH)
Anxiety Disorders
Major Depressive Disorder
Study Description:
This study examines relations between neurocognitive and clinical features of pediatric
anxiety disorders. The study uses neuro-cognitive tasks, functional magnetic resonance
imaging (fMRI), as well as magneto- and electro-encephalography (M/EEG). Patients will be
studied over... expand
Study Description: This study examines relations between neurocognitive and clinical features of pediatric anxiety disorders. The study uses neuro-cognitive tasks, functional magnetic resonance imaging (fMRI), as well as magneto- and electro-encephalography (M/EEG). Patients will be studied over one year, before and after receiving either one of two standard-of-care treatments: cognitive behavioral therapy (CBT) or fluoxetine, a serotonin reuptake inhibitor (SSRI). Healthy comparisons will be studied at comparable time points. Primary Objectives: To compare healthy youth and symptomatic, medication-free pediatric patients studied prior to receipt of treatment. The study seeks to detect relations between clinical features of anxiety disorders at baseline and a wide range of neurocognitive features associated with attention, memory, and response to motivational stimuli. Secondary Objectives: 1. To document relations between baseline neurocognitive features and response to Cognitive Behavioral Therapy (CBT) or fluoxetine, as defined by the Pediatric Anxiety Rating Scale (PARS) and Clinical Global Improvement (CGI) Scale. 2. To document relations between post-treatment changes in neurocognitive features and anxiety symptoms on the PARS following treatment with Cognitive Behavioral Therapy (CBT) or fluoxetine. 3. To document relations among broad arrays of clinical, cognitive, and neural measures Primary Endpoints: Indices of percent-signal change in hypothesized brain regions, comprising amygdala, striatum, and prefrontal cortex (PFC) for each fMRI and MEG paradigm. Secondary Endpoints: 1. Treatment-response as defined by a continuous measure, the Pediatric Anxiety Rating Scale score (PARS), and a categorial measure, the Clinical Global Improvement (CGI) score. 2. Levels of symptoms and behaviors evoked by tasks that engage attention, memory, and elicit responses to motivational stimuli. Type: Interventional Start Date: Oct 2001 |
Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder (PALISADE-4)
VistaGen Therapeutics, Inc.
Social Anxiety Disorder (SAD)
This U.S. Phase 3 clinical trial is designed to evaluate the efficacy, safety, and
tolerability of the acute intranasal (i.n.) administration of Fasedienol Nasal Spray
(fasedienol) (3.2 µg) to relieve symptoms of acute anxiety in adult subjects ages 18
through 65 with Social Anxiety Disorder induced... expand
This U.S. Phase 3 clinical trial is designed to evaluate the efficacy, safety, and tolerability of the acute intranasal (i.n.) administration of Fasedienol Nasal Spray (fasedienol) (3.2 µg) to relieve symptoms of acute anxiety in adult subjects ages 18 through 65 with Social Anxiety Disorder induced by a public speaking challenge (PSC) in a clinical setting. In addition, safety and tolerability of i.n. administration of 3.2 µg of fasedienol, as-needed, up to 6 times per day for up to 12 months, will be assessed in those subjects who complete PALISADE-4 and choose to enter the distinct open-label extension phase of the study. Type: Interventional Start Date: Sep 2024 |
Community Park-Based Programs for Health Promotion: Fit2Play Prospective Cohort Study
Duke University
Overweight
Obesity
Hypertension
Prehypertension
Anxiety
The Fit2Play prospective cohort study examines the effects of a park-based youth physical
activity afterschool program on youth participant fitness and mental health outcomes.
Duke will perform a secondary analysis of the data collected as part of the Fit2Play
prospective cohort study run by Miami-Dade... expand
The Fit2Play prospective cohort study examines the effects of a park-based youth physical activity afterschool program on youth participant fitness and mental health outcomes. Duke will perform a secondary analysis of the data collected as part of the Fit2Play prospective cohort study run by Miami-Dade County Parks and Recreation. Type: Observational Start Date: May 2020 |
FMRI Accelerated TMS Depression
Medical University of South Carolina
Depression
This study aims to investigate whether phenotypic-related brain states revealed by a
novel INSCAPE ("Individualized Network-based Single-frame Coactivation Pattern
Estimation") neuroimaging method in Major Depressive Disorder (MDD) patients can track
brain recovery of MDD patients over an accelerated... expand
This study aims to investigate whether phenotypic-related brain states revealed by a novel INSCAPE ("Individualized Network-based Single-frame Coactivation Pattern Estimation") neuroimaging method in Major Depressive Disorder (MDD) patients can track brain recovery of MDD patients over an accelerated antidepressant transcranial magnetic stimulation (TMS) treatment. Type: Observational Start Date: Sep 2024 |
Postpartum Care in the NICU (PeliCaN) Transitions
University of Pennsylvania
Stress Disorders, Post-Traumatic
Premature Birth
Postpartum Depression
Postpartum Anxiety
This is a randomized controlled trial of a dyad-centered, doula support and healthcare
coordination model of care in a large urban neonatal intensive care unit (NICU), which
serves a high-risk, low-income, majority Black population. In addition to doula support
and coordination of care in the NICU,... expand
This is a randomized controlled trial of a dyad-centered, doula support and healthcare coordination model of care in a large urban neonatal intensive care unit (NICU), which serves a high-risk, low-income, majority Black population. In addition to doula support and coordination of care in the NICU, there will be a warm handoff to a community doula to continue the support once infants leave the Hospital of the University of Pennsylvania (HUP) NICU. Type: Interventional Start Date: Sep 2024 |
Massage for GAD: Neuroimaging and Clinical Correlates of Response
University of Utah
Generalized Anxiety Disorder
This clinical trial will compare the effects of Swedish massage or light touch therapy on
brain activity and symptoms of anxiety.
This is a randomized research study and subjects will be randomized into one of two study
touch intervention groups, and will have an equal chance of being placed in... expand
This clinical trial will compare the effects of Swedish massage or light touch therapy on brain activity and symptoms of anxiety. This is a randomized research study and subjects will be randomized into one of two study touch intervention groups, and will have an equal chance of being placed in one of the groups: 1. Swedish massage therapy twice per week for 6 weeks. 2. Light touch therapy twice per week for 6 weeks. The Primary Objective is to identify brain networks activated by touch interventions using fMRI brain imaging in subjects with generalized anxiety disorder. Subjects will undergo two fMRI scanning sessions (one before and one after) twice per week for 6 weeks of touch intervention. Subjects will also be asked to complete questionnaires on anxiety, stress and depression. Type: Interventional Start Date: May 2024 |
Feasibility of a Prenatal Yoga Mobile App in African American Pregnant Women
San Diego State University
Pregnancy Related
Mental Health Issue
Discrimination, Racial
Stress
Depression
The goal of this research is to test if a prenatal yoga app can improve well-being in
African American/Black (AA) pregnant women. The main questions it aims to answer are:
1. Is the Down Dog prenatal yoga app feasible for AA pregnant women?
2. How does mental and physical health change after... expand
The goal of this research is to test if a prenatal yoga app can improve well-being in African American/Black (AA) pregnant women. The main questions it aims to answer are: 1. Is the Down Dog prenatal yoga app feasible for AA pregnant women? 2. How does mental and physical health change after using the Down Dog app for 12-weeks? 3. What cultural adaptations to the Down Dog app are needed? The study lasts for 12 weeks and participants are asked to: - do prenatal yoga with the app for at least 20 min/day, three days/week, from home - wear a Garmin Vivosmart 5 watch daily - complete four online surveys - complete an optional virtual interview This project aims to advance public health by contributing to a broader understanding of how prenatal yoga can support the health and well-being of AA pregnant women and promote optimal maternal and child health outcomes. Type: Interventional Start Date: Oct 2024 |
Tele-PROTECT Therapy: Effectiveness, Empowerment, and Implementation
Weill Medical College of Cornell University
Depression
Elder Abuse
The purpose of this randomized trial is to conduct a fully powered effectiveness trial of
video-delivered PROTECT (Tele-PROTECT) compared to a video-delivered depression education
(DepEd) control condition to be delivered to 140 English- and Spanish-speaking NYC elder
abuse victims. Investigators... expand
The purpose of this randomized trial is to conduct a fully powered effectiveness trial of video-delivered PROTECT (Tele-PROTECT) compared to a video-delivered depression education (DepEd) control condition to be delivered to 140 English- and Spanish-speaking NYC elder abuse victims. Investigators hypothesize three main aims: 1. Effectiveness Aim: Tele-PROTECT participants will have significantly greater and clinically meaningful reductions in depression when compared to the DepEd control; 2. Abuse Impact Aim: Tele-PROTECT participants will demonstrate greater safety related empowerment compared to DepEd control, which can help participants take steps to reduce risk; 3. Implementation Aim: Stakeholders' views of the factors impacting the implementation of Tele-PROTECT based on characteristics of the intervention, agency setting, and population served will contribute to a national dissemination of Tele-PROTECT Participants will - Receive 9 weeks of tele health psychotherapy delivered by a Master's level mental health clinician from the Weill Cornell Medicine research team. Participants will be assigned to "Tele-PROTECT" or "DepEd" psychotherapy randomly. - Participate in one baseline assessment and four follow-up assessments at weeks 3, 6, 9, and 12 administered by a trained member of the research team. Type: Interventional Start Date: Sep 2023 |
- Previous
- Next