Improving Outcome in Schizophrenia Through Identification of Genetic Risk Factors
Purpose
The goals of this study are to replicate previous findings of genetic predictors of response to clozapine and other antipsychotic drugs.
Conditions
- Schizophrenia
- Schizoaffective Disorder
- Bipolar Disorder
- Major Depression
Eligibility
- Eligible Ages
- Between 18 Years and 65 Years
- Eligible Genders
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
Patients with the diagnoses of schizophrenia or schizoaffective disorder, and bipolar disorder or major depression with psychotic features, or volunteers with no history of a psychotic disorder.
Exclusion Criteria
Patients with DSM-IV diagnoses other than schizophrenia or schizoaffective disorder, and bipolar disorder or major depression with psychotic features.
Study Design
- Phase
- N/A
- Study Type
- Interventional
- Allocation
- Non-Randomized
- Intervention Model
- Single Group Assignment
- Primary Purpose
- Diagnostic
- Masking
- None (Open Label)
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
|
Active Comparator 1 Outcome in schizophrenia with certain antipsychotic |
clozapine |
|
|
Active Comparator 2 Outcome in schizophrenia with other Antipsychotics |
Other Antipsychotics |
|
Recruiting Locations
More Details
- Status
- Recruiting
- Sponsor
- Northwestern University
