Engage for Late-Life Depression and Comorbid Executive Dysfunction
Purpose
Although there are an increasing number of mental health treatment adaptations for older adults, there are still a number of factors to consider when making these adaptations. Cognitive decline is one such factor that places significant burden on older adults and can interfere with traditional mental health therapies. Engage is a behavioral treatment approach that has shown to be effective in treating late life depression. The investigators are testing the feasibility of Engage as a treatment method for late life depression in older adults with cognitive decline. The objective is to corroborate Engage as an alternative late life depression treatment method for a sub-population of older adults with cognitive decline. Cognitive decline poses a unique mental health treatment barrier that is often over looked in younger populations. With a relatively higher prevalence of cognitive decline in older adulthood, it is imperative that a feasible mental health treatment program that can be effective in the presence of cognitive decline.
Conditions
- Depression in Old Age
- Psychotherapy
- Mild Cognitive Impairment
- Executive Dysfunction
Eligibility
- Eligible Ages
- Over 60 Years
- Eligible Genders
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- Age 60 or older - Ability to read, write, and speak English - Located in Las Vegas or surrounding area - Ability to travel to UNLV campus by self or possible caregiver for regular study visits - Clinically significant symptoms of depression as evidenced by: 1) Scores > 5 on the Geriatric Depression Scale-Short Form (GDS-SF) - Mild cognitive impairment as evidenced by: 1) Scores > 18 and < 25 on the Montreal Cognitive Assessment (MoCA)
Exclusion Criteria
- Active suicidal ideation - History of suicide attempt(s) - Current symptoms of: 1) Psychosis; 2) Active substance use disorder - Reported history of: 1) Bipolar disorder ("manic depression"); 2) Intellectual disability - Currently in or scheduled to initiate individual psychotherapy to avoid treatment interference - Psychotropic medication permitted if dose was stable over the past 2 weeks - Currently living in an institutional setting (e.g., assisted living, inpatient, skilled nursing) - Presence of notable memory-specific cognitive deficits as evidenced by: scores < 9 on the MoCA memory subscale (rendering it difficult to participate in and track/recall events for weekly psychotherapy)
Study Design
- Phase
- N/A
- Study Type
- Interventional
- Allocation
- N/A
- Intervention Model
- Single Group Assignment
- Intervention Model Description
- The trial will be a single-arm feasibility trial of Engage for treatment of late-life depression in older adults with comorbid executive/cognitive dysfunction.
- Primary Purpose
- Treatment
- Masking
- None (Open Label)
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
|
Experimental Engage Treatment |
The study is a single-arm study. The single-arm will be implementation of the 9-week protocol of Engage in an older adult population with late-life depression and comorbid executive dysfunction and mild cognitive impairment. |
|
Recruiting Locations
More Details
- Status
- Recruiting
- Sponsor
- University of Nevada, Las Vegas
