Anxiety & Depression Association of America

Text -Based Depression Screening Among Cancer Survivors

Purpose

Depression is common among cancer survivors, but current screening methods are not always effective. To help improve depression screening for cancer survivors, this study will conduct a pilot randomized controlled trial (RCT) with 60 participants. The goal is to evaluate whether a text message-based approach to depression screening is feasible, acceptable, and potentially more effective than the current standard of care.

Conditions

Cancer
Depression Secondary to Other Disease
Cancer Survivor

Eligibility

Eligible Ages: Over 18 Years
Eligible Sex: All
Accepts Healthy Volunteers: No

Criteria

Inclusion Criteria:

- age > 18 years

- diagnosis of cancer

- upcoming appointment in an HCC or HCN oncology clinic within 14 days

- English proficiency

- ownership of a cellphone with SMS text capability.

Study Design

Phase: N/A
Study Type: Interventional
Allocation: Randomized
Intervention Model: Parallel Assignment
Primary Purpose: Supportive Care
Masking: Single (Investigator)

Arm Groups

Arm	Description	Assigned Intervention
Experimental Text-Based Depression Screening		Behavioral: Text-based depression screening Starting 1 week prior to the scheduled clinic appointment, patients will receive a text message invitation from HCC to complete depression screening. Participants will be asked to click to continue to the screening PHQ-2. For text message screening cadence, reminder texts will be sent daily for 3 days. Those who screen positive (PHQ-2 >/= 3) will complete the remainder of the items (i.e., PHQ-9).
Active Comparator Usual Care		Behavioral: Usual care (UC) Usual care (UC) will consist of in-person assessment of depression using a validated brief screening tool (e.g., PHQ-2) synchronous with a clinical encounter with the outpatient oncology team. Although the person completing the screening (e.g., nurse, medical assistant) and other workflow may vary slightly across settings, the 2-items are generally presented orally to the patient during routine intake for a clinical encounter and entered into the EHR. Patients who screen positive will be asked to complete the full PHQ-9.

Recruiting Locations

More Details

Status: Recruiting
Sponsor: Medical University of South Carolina

Study Contact

Ruby H McGhee, B.A. Psychology
919-727-2339
mcgheeru@musc.edu

Detailed Description

This pilot randomized controlled trial aims to evaluate the feasibility, acceptability, and preliminary efficacy of a text message-based depression screening approach for cancer survivors. A total of 60 adult cancer survivors will be enrolled and randomly assigned to either the text message intervention or the usual care depression screening. The intervention involves sending text messages one week before scheduled oncology appointments, inviting participants to complete a depression screening using the PHQ-2, followed by the PHQ-9 for those who screen positive. The study will assess the feasibility of implementing text message-based screenings, participant acceptability, and compare the efficacy of this method to traditional in-person depression screenings during clinical visits. The primary outcome is feasibility, measured by the proportion of participants completing the screening via text, while secondary outcomes will include acceptability (assessed through participant surveys) and preliminary efficacy (measured by screening completion rates and depression detection). Eligible participants will be English-speaking cancer survivors aged 18 or older with an upcoming oncology appointment at the Hollings Cancer Center or associated clinics. The study aims to improve current depression screening methods and address challenges such as logistical and system-level barriers in screening cancer survivors for depression.