Purpose

The purpose of the proposed pilot study is to extend previous findings regarding the efficacy of a brief treatment for chronic posttrauma nightmares and sleep problems by integrating this treatment with evidence-based treatment for posttraumatic stress disorder (PTSD). Cognitive processing therapy (CPT) (Resick & Schnicke, 1996) is a well-established and efficacious evidence-based psychological treatment for PTSD in both civilian and veteran populations (Forbes et al., 2012; Monson et al., 2006; Resick et al., 2008; Resick, Nishith, Weaver, Astin, & Feuer, 2002). The U.S. Department of Veterans Affairs (VA) includes CPT among the first-line treatments for PTSD (National Center for PTSD, 2012). A modified protocol without the utilization of written exposure (CPT-C) may be more effective than the original protocol. However, despite such promising evidence, individuals who experience chronic nightmares and sleep problems tend to show smaller gains and persistent nightmares following PTSD treatment (Nappi, Drummond, & Hall, 2012). Given that nightmares are considered the hallmark of PTSD (Ross, Ball, Sullivan, & Caroff, 1989) and their treatment-resistant nature (Davis & Wright, 2007), specific psychological treatments have been developed to target sleep disturbances and nightmares. Exposure, relaxation, and rescripting therapy (ERRT) is a promising psychological intervention developed to target trauma-related nightmares and sleep disturbances. Though further evidence is needed, ERRT has exhibited strong support in reducing the frequency and intensity of nightmares, as well as improving overall sleep quality in both civilian and veteran samples. In addition, significant decreases in PTSD and depression symptoms have been reported following treatment (Davis et al., 2011; Davis & Wright, 2007; Long et al., 2011; Swanson, Favorite, Horin, & Arnedt, 2009). ERRT is currently an evidence-level B suggested treatment (Cranston, Davis, Rhudy, & Favorite, 2011). There is a call to research suggesting the importance of treatment studies which focus on interventions that integrate nightmare and sleep symptom treatment with evidence-based treatment for PTSD (Nappi et al., 2012). In an effort to respond to this call, we propose to tailor ERRT for use in conjunction with CPT, and preliminarily test ERRT's additive effect to CPT in treating PTSD in community outpatients. We hypothesize that ERRT would increase CPT's treatment efficacy by its specific focus on trauma-related nightmares and sleep disturbances. Sleep difficulties are known to increase tension, and reduce one's ability to cope adaptively (Bonn-Miller, Babson, Vujanovic, & Feldner, 2010; Hofstetter, Lysaker, & Mayeda, 2005; Nishith, Resick, & Mueser, 2001). Thus, with improved sleep an individual may have additional personal coping resources for which s/he can use to address the broader trauma issues (Nappi et al., 2012). To test this integration, we will compare ERRT + CPT, CPT + ERRT, and CPT alone.

Conditions

Eligibility

Eligible Ages
Over 18 Years
Eligible Genders
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • 18 Years of Age minimal - Experienced a trauma - One nightmare per week for past month, minimal - meet full criteria for PTSD

Exclusion Criteria

  • 17 years of age or younger - acute psychosis - bipolar disorder - intellectual disability - active suicidality - untreated substance use disorder within past 6 months

Study Design

Phase
N/A
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Primary Purpose
Treatment
Masking
Single (Outcomes Assessor)

Arm Groups

ArmDescriptionAssigned Intervention
Active Comparator
Cognitive Processing Therapy-Cognitive
12 sessions of cognitive processing therapy-Cognitive
  • Behavioral: Cognitive Processing Therapy - Cognitive
    12 sessions cognitive behavioral treatment targeting posttraumatic stress symptoms.
    Other names:
    • CPT-C
    • CPT
Active Comparator
ERRT + CPT-C
5 sessions of Exposure, Relaxation, and Rescripting Therapy, followed by 12 sessions of Cognitive Processing Therapy- Cognitive
  • Behavioral: Exposure, Relaxation, and Rescripting Therapy
    5 sessions that last approximately one hour addressing nightmares and sleep problems. Participants will log sleep events and associated symptoms
    Other names:
    • ERRT
    • IRT
  • Behavioral: Cognitive Processing Therapy - Cognitive
    12 sessions cognitive behavioral treatment targeting posttraumatic stress symptoms.
    Other names:
    • CPT-C
    • CPT
Active Comparator
CPT-C + ERRT
12 sessions of Cognitive Processing Therapy - Cognitive, followed by 5 sessions of Exposure, Relaxation, and Rescripting Therapy
  • Behavioral: Exposure, Relaxation, and Rescripting Therapy
    5 sessions that last approximately one hour addressing nightmares and sleep problems. Participants will log sleep events and associated symptoms
    Other names:
    • ERRT
    • IRT
  • Behavioral: Cognitive Processing Therapy - Cognitive
    12 sessions cognitive behavioral treatment targeting posttraumatic stress symptoms.
    Other names:
    • CPT-C
    • CPT

Recruiting Locations

More Details

Status
Recruiting
Sponsor
University of Tulsa

Study Contact

Joanne L Davis, PhD
9186312875
joanne-davis@utulsa.edu

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.