Post-Traumatic Stress Disorder Focused Psychodynamic Psychotherapy
Purpose
This is a randomized controlled trial of Trauma-Focused Psychodynamic Psychotherapy (TFPP) in comparison with TAU (at the VA) in a 2:1 ratio in 75 Veterans with PTSD who have not responded to standard treatment at the VA.
Condition
- PTSD
Eligibility
- Eligible Ages
- Between 18 Years and 70 Years
- Eligible Genders
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- Reporting moderate PTSD, as defined by a CAPS score of >40 - Have at least one of the following history with CPT and/or PE: - offered and declined - dropped out of treatment - been determined unsuitable by their treatment team - received treatment but continue to experience symptoms meeting entrance criteria. - Require stabilization on psychiatric medication for 2 month period prior to entry into study to avoid confounding treatments
Exclusion Criteria
- Presence of SCID-5 assessed psychotic disorder, bipolar disorder, or substance use that would interfere with trial demands - Severe suicidality that would require immediate crisis management - Organic mental syndromes, delirium, or unstable medical conditions that would interfere with trial demands - Inability to meet trial demands.
Study Design
- Phase
- N/A
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel Assignment
- Intervention Model Description
- Randomized controlled trial of psychosocial interventions
- Primary Purpose
- Treatment
- Masking
- Single (Outcomes Assessor)
- Masking Description
- All assessments will be performed by blinded clinical assessors; randomization accomplished by computer algorhythm
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
|
Experimental TFPP |
TFPP is a manualized 16-24 session psychodynamic psychotherapy targeted on trauma symptoms of PTSD |
|
|
Active Comparator TAU |
TAU in this study is treatment for PTSD as currently delivered at the VA |
|
Recruiting Locations
More Details
- Status
- Recruiting
- Sponsor
- Montefiore Medical Center
Detailed Description
Veterans with PTSD are a highly vulnerable population with tremendous disability and unmet needs. Few VA patients with PTSD now actually receive evidence-based psychotherapy because current exposure-based treatments have low uptake. The project goal is to expand the range of PTSD psychotherapy treatments available at Veterans Administration Medical Centers. This pilot trauma recovery proposal takes the next step in translating a brief efficacious psychotherapy developed and tested for panic disorder, Panic Focused Psychodynamic Psychotherapy (PFPP) for Veterans with PTSD at the VA New York Harbor Healthcare System (VA NYHHCS). PFPP was developed, manualized, and studied in RCTs over the past two decades. We hope that Trauma-Focused Psychodynamic Psychotherapy (TFPP), an adaptation of PFPP, with its high response rates in panic disorder with/without agoraphobia, and non-exposure protocol, will fill crucial gaps in Veteran care. A major challenge facing psychotherapy research is translating and implementing efficacious therapies to the community. No psychodynamic psychotherapy for anxiety or PTSD has achieved this in the US. This pilot RCT represents a paradigm shift in its approach to trauma. TFPP will be the only PTSD treatment for Veterans to incorporate Veterans' input into refinement of the treatment as this project progresses. TFPP targets aspects of traumatic experience and approaches Veterans' lives more broadly than the symptom-focused treatments the VA currently offers our traumatized Veterans.
