Anxiety & Depression Association of America

Improving Outcome in Schizophrenia Through Identification of Genetic Risk Factors

Purpose

The goals of this study are to replicate previous findings of genetic predictors of response to clozapine and other antipsychotic drugs.

Conditions

Schizophrenia
Schizoaffective Disorder
Bipolar Disorder
Major Depression

Eligibility

Eligible Ages: Between 18 Years and 65 Years
Eligible Genders: All
Accepts Healthy Volunteers: Yes

Inclusion Criteria

Patients with the diagnoses of schizophrenia or schizoaffective disorder, and bipolar disorder or major depression with psychotic features, or volunteers with no history of a psychotic disorder.

Exclusion Criteria

Patients with DSM-IV diagnoses other than schizophrenia or schizoaffective disorder, and bipolar disorder or major depression with psychotic features.

Study Design

Phase: N/A
Study Type: Interventional
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Primary Purpose: Diagnostic
Masking: None (Open Label)

Arm Groups

Arm	Description	Assigned Intervention
Active Comparator 1 Outcome in schizophrenia with certain antipsychotic	clozapine	Procedure: genetic analysis genetic assay of blood sample drawn with patient's consent Procedure: genetic assay genetic assay of blood sample drawn with patient's consent
Active Comparator 2 Outcome in schizophrenia with other Antipsychotics	Other Antipsychotics	Procedure: genetic analysis genetic assay of blood sample drawn with patient's consent Procedure: genetic assay genetic assay of blood sample drawn with patient's consent

Recruiting Locations

More Details

Status: Recruiting
Sponsor: Northwestern University

Study Contact

Barrett Share, M.A.
615-936-6796
daniel.b.share@vanderbilt.edu

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.